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The 2nd glutathione-interaction site appears to preferentially interact with the -glutamylcysteinyl moiety of GSH and is thought to facilitate the recruitment and activation of GSH as a preferred reducing agent 7,11,13,17,50

However, unlike DESI-MSI, MALDI-MSI typically produces singly-charged ions, significantly simplifying mass spectra and facilitating data analysis

Moreover, they found no significant correlation between TMAO and mitochondrial DNA copy number