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The urea cycle is also regulated by N -acetylglutamate (NAG), which is necessary for the activation of CPS1 [2]

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Notably, a marked accumulation of an unchanged concentration of METH has been shown in METH-sensitized rat brain cortex, striatum, and heart, but not in the liver, kidney, or abdominal muscle, following a bolus injection of 4 mg/kg METH, demonstrating a viable reason for the higher toxicity METH use poses to cardiac tissue 47

Reduced frontal activation during verbal fluency task in chronic hepatitis C patients with interferon-based therapy as measured by near-infrared spectroscopy
