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In contrast, M(Hb) and Mhem macrophages activated by hemoglobin and haeme, respectively, play more atheroprotective roles attributed to their prevention of foam cell formation and lipid accumulation by promoting the expression of reverse cholesterol transport-associated genes, such as liver X receptor alpha (LXR) and ATP-binding cassette transporters A1 (ABCA1) [96, 97]
Pickart i Margolina 2018)
Nat Chem Biol 13(1):8190 Ye Z et al (2020) Abrogation of ARF6 promotes RSL3-induced ferroptosis and mitigates gemcitabine resistance in pancreatic cancer cells
J Stroke Cerebrovasc Dis 2009;18:319-28
