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Description
Human evidence is limited to three small pilot studies (fewer than 30 total subjects) covering interstitial cystitis, knee pain, and IV safety, none with placebo controls

Thus, it appears important to evaluate vitamin B 12 status, as well as kidney function, in older individuals with elevated homocysteine levels prior to initiating homocysteine-lowering therapy

10.1016/j.yexcr.2012.01.020

An inhibitor is a compound that blocks this enzymes activity
