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These inflammatory mediators decrease CYP19A1 expression, activate the NF-B/NLRP3 inflammasome, and aid in the activation of insulin receptor Ser307 via the JNK pathway ( However, the small sample size limits precision in local cytokine quantification

PMID: 27 CotaVSohrabiSKaletskyRMurphyCT

It also has a direct impact on several biological processes, such as short-chain fatty acid (SCFA) oxidation, and triglyceride (TG) degradation 102,103,104

While BSO exhibits some anti-tumor activity, its clinical investigation is still very limited, necessitating additional research to determine its safety and efficacy in cancer therapy