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(2023) stated that liver sinusoidal endothelial cells, being most vulnerable to damage, secrete damage-associated molecular patterns (DAMPs) dominated by HMGB1 to impact the whole liver microenvironment

Berberine is not the same as Metformin, though, and it should not be treated as a replacement for prescribed medication

The zeta potential of niosomes lied in a range that exhibits high stability owing to electrostatic repulsion
