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Description
Investigators proceeded with supplementation with folic acid (350 to 1,000 g daily by mouth) and vitamin B12 (1,000 g IM every 9 weeks) in 220 patients receiving chemotherapy with pemetrexed disodium
It also activates integrin-linked kinase (ILK) for tissue repair signaling

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4 However, the elevated risk was observed specifically among male current smokers
