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In a transgenic model of AD, SAMe administration reversed DNA hypomethylation, including at the BACE1 promoter (51), leading to decreased A accumulation and cognitive improvements

When the total amount of antibody is kept constant but the volume of the reaction is reduced 10 times (from 500 L to 50 L), the binding of the antibody is about 30% better

[DOI] [PMC free article] [PubMed] [Google Scholar] 42.Coeffier M, Claeyssens S, Hecketsweiler B, Lavoinne A, Ducrotte P, Dechelotte P