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Description
When symptoms occur, they typically relate to underlying conditions such as liver disease, kidney dysfunction, or haematological disorders that cause the elevation, rather than the high B12 itself
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There is around a 2.5-fold increase in B12 deficiency incidence in those treated with metformin, and this may occur as early as 3 months, although hepatic stores of vitamin B12 may take 5 years or more to deplete (Bell, 2022)
H., Noel, E., Kaltenbach, G., Abdelgheni, M