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In animal studies, MT has been shown to mitigate oxidative stress, apoptosis, and cardiac dysfunction induced by high glucose and STZ by modulating the AMPK/SIRT1 signaling pathway (Wang et al., 2021)

4.2 Negative implication As previously described, ROS in plants at low or moderated intensities function as signalling molecules in the regulation of normal plant growth as well as in acclimation under stressful conditions

Notice that CBS fluxes do not differ much between males and females, so this is not the reason that GSH differs so dramatically in males and females