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Figure EV2 Abscopal effect of radiotherapy enhanced by poly(I:C) stimulated tumor ferroptosis

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[193] proposed a novel NIR light-triggered photothermal polymer containing DAP-F complexed with a reduction-sensitive amphiphilic polymer, P1, to form F-nanoparticles with photothermal effects that can encapsulate Pt(IV) prodrugs via P1 and bind F-nanoparticles to Pt-nanoparticles to construct the final nanosystem F-Pt-nanoparticles, which inhibited DNA repair, effectively overcame cisplatin resistance, and suppressed tumors (Figure 5)

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