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Figure 10 Claudin-5 is the primary regulator of BBB impermeability and is the main claudin isoform examined in our studies (Greene et al., 2019)

References Akaltun I, Kara SS, Kara T (2018) The relationship between toxoplasma gondii IgG antibodies and generalized anxiety disorder and obsessive-compulsive disorder in children and adolescents: a new approach

This favorable safety margin provides reassurance, though extrapolation from animals to humans always involves uncertainty

Single genes encode NR and NiR in algae, excepting some particular cases as Coccomyxa subellipsoidea C-169, which has two NRs in its genome (Table 1)
