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RNA-seq analysis RNA-seq was performed for Macrogen Japan Incorporated (Kyoto, Japan)

The copper-induced demise involves a protein lipoylation process, a rare and highly conserved lysine post-translational modification, which has only been observed in four lipoylated protein complexes in mammals: pyruvate dehydrogenase (PDH), alpha-ketoglutarate dehydrogenase (KDH), branched-chain alpha-keto acid dehydrogenase (BCKDH), and the glycine cleavage system (GCV) (89)

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Clinical Context Epitalon should not be described as a cancer treatment or cancer cure