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Description
This leads to the generation and expansion of immunosuppressive cell populations within the tumor microenvironment (TME), including myeloid-derived suppressor cells (MDSCs) and, critically, regulatory Treg cells ( TME Remodeling and Metastasis: HLA-G expression is not just a defensive shield
In addition, the development of immunopeptidome analysis should provide successful targets and open the way to a new generation of senolytic treatments
Derosa et al., 2016
This triggers a pulsatile GH release, closely resembling the body's natural secretion patterns
