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Description
In wounded tissue, nociceptive signaling is not merely a consequence of direct activation of peripheral nerves by trauma but arises from a dynamic interplay between immune, inflammatory, and neural components of the tissue microenvironment
While not dangerous, they indicate significant vascular reactivity and suggest the nitric oxide system is responding robustly to the peptide
In the human obesity program, AOD-9604 was generally reported to be well tolerated over the studied durations, with a safety profile that avoided the endocrine concerns associated with full-length growth hormone
2017 Oct
