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The results of early clinical trials with ARO-ANG3 demonstrated reductions in circulating levels of ANGPTL3 of up to 84%, reductions in circulating triglyceride levels of up to 58%, and reductions of non-HDL cholesterol of up to 26%

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doi: 10.1016/j.anndiagpath.2015.10.009
Yes, by improving fat utilization, it helps provide sustained energy during workouts, especially cardio and endurance training
