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The second stage is the final treatment, where pretreated water enters reverse osmosis membranes before passing through an Electrodeionization (EDI) module or other deionization process

Modifications of the inner lumen of the artificial conduits with physical cues that could potentially guide the regenerative process in a confined environment is highly appealing (de Luca et al., 2014

Human clinical trials on Mesenchymal Stem Cells (MSCs) have reported promising outcomes exhibited by MSCs in reducing pain and improving function

Two strategies may be useful to move the field forward