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This effect is associated with inhibited oncogenic activity of AKT and MYC, as well as Bax phosphorylation, suggesting that PP2A may also be a potential metformin target in lung cancer therapy
Moreover, iron overload-induced gasdermin E (GSDME)-mediated pyroptosis can trigger the activation and release of IL-16, which drives inflammation in ovarian endometriosis through CD4 + T cells
10.1016/j.nbd.2019.104681 155 SinghV.XuL.BoykoS.SurewiczK.SurewiczW
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