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Furthermore, intestinal flora dysfunction is a causative agent of CRC by following mechanisms: 1) Flora with its infiltrating metabolites (including secondary bile acids, H2S and NOCs) promotes inflammation, which influences initiation, promotion and progression of carcinogenesis

Mechanism summary sourced from pep-pedia.org and the published peptide research literature

Betaine ameliorates depressive-like behaviors in zinc oxide nanoparticles exposed mice

Dai et al, 2020), which could explain favoring of nonmesodermal cell lineages in organoids upon loss of Nrf2 expression