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Perimenopause and hormonal decline are among the most common and least recognized drivers of new-onset GI symptoms in women over 35 bloating, IBS-like symptoms, and increased gut reactivity often emerge alongside hormonal shifts

Its primarily in the Liver, Yes - but there are much smaller stores elsewhere for " local" processing...these are not part of the digestive process

Several viruses can cause a post-viral infection fatigue syndrome that can cause significant lack of energy

[282] The US Food and Drug Administration (FDA) and the Centers for Disease Control and Prevention (CDC) authorized the use of an additional mRNA vaccine dose for immunocompromised individuals at that time