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Temozolomide is an oral alkylating agent that crosses the blood-brain barrier and is primarily used in glioblastoma and anaplastic astrocytoma

Youn HS, Kim YS, Park ZY, Kim SY, Choi NY, Joung SM, et al

The procedure involves about five or six relatively painless injections and patients start feeling the effects the following day with migraines usually dissipating by the end of the first week
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