excess glutathione toxicity Oxidative Stress Early After Hematopoietic Stem Cell Transplant Transplantation and Cellular Therapy Tumor-targeted glutathione oxidation catalysis with
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Zhang C, Filella I, Liu D, Ogaya R, Llusi J, Asensio D, et al
Abstract Overproduction of reactive oxygen species occurs when inflammation induces oxidative stress in macrophages and microglia, leading to a self-sustaining cycle of cellular damage and neuroinflammation
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It has been proposed that the pathophysiology of IIM could be attributed to increased cell death, inadequate removal of cell debris, and excessive autoantigens and pro-inflammatory cytokines, which eventually result in over-stimulated immunological and inflammatory responses (152)
