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This is the mechanism behind prion diseases (such as Creutzfeldt-Jakob disease), and it leads to aggregation of both the mutant and the wild-type molecules
[DOI] [PubMed] [Google Scholar] Tanaka T, Ikita K, Ashida T, Motoyama Y, Yamaguchi Y, et al
(I received this product in order to evaluate it and give my opinion, but rest assured that my comments are always honest and impartial.)
and a highly polar or charged group is attached through a phosphodiester linkage to the third carbon
