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Neuroimaging studies have shown a reduction in hippocampal volume and abnormal prefrontal cortical activity, which strongly correlates with impairments in verbal memory and information processing speed ( 2.3.2 Psychiatric symptoms METH abuse disrupts the functionality of various brain regions, including the prefrontal cortex, nucleus accumbens, and thalamus, leading to significant psychiatric disturbances (Sekine et al., 2001)

Fekete, M., Lehoczki, A., Tarantini, S., Fazekas-Pongor, V., Csp, T., Csizmadia, Z., & Varga, J

Smith JF, Walsh TJ, Conti SL, Turek P, Lue T

Assays for the identification and prioritization of drug candidates for spinal muscular atrophy