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This inherent limitation may have influenced subjective symptom reporting and contributed to variations in OSDI outcomes across studies

Therapeutic targeting of autophagy has shown potential for overcoming drug resistance (Chang and Zou 2020)

These findings suggested that the MAPK pathway and MMPs/TIMPs imbalance played a role in NiO NPs -induced excessive collagen formation

In summary, omega-3 fatty acids interfere with the normal operation of multiple signaling pathways, including EGFR and PI3K/Akt, by remodeling the lipid composition and microstructure of cell membranes, inhibiting proliferation and survival signals, and enhancing apoptotic signals in tumor cells