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Molecular Psychiatry, 2013.18(11): p
doi: 10.1007/s40263-015-0300-9
In addition, as mitochondrial diseases particularly affect tissues and cells that are highly dependent on mitochondrial energy production (such as neuronal, muscle and cardiac cells) (Pfeffer et al., 2013), the use of brain organoids to study the role of mitochondria in neurodevelopmental disorders is a revolutionary strategy
See also a discussion on false negative target predictions in Additional file 1
