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Concurrent administration of the two peptides is thus believed to have more potent healing effects, with research suggesting a synergistic effect to accelerate the migration of fibroblasts and immune system cells to sites of injury [8, 9, 11]

The evidence is unclear or shows little to no benefit from using B12 supplementation, but more research is needed in these areas

Borron SW, Baud FJ

For the construction of the metE mutant, the AES -which contained a Kan R cassette and the GFP gene optimized for its expression in mycobacteria (eGFP) (Supplementary Note 1)- was synthesized by GenScript