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3 linked pagesOpen original pubmed-heffernan-aod9604-2001 AOD-9604 Clinical Trial Registry Entries: ClinicalTrials.gov ClinicalTrials.gov / U.S

10.1021/bi200614y Biochemistry 73 ReinwarthM.AvrutinaO.FabritzS.KolmarH
& McCoy, C.E

G6PD-deficient cells are unable to generate enough NADPH under the condition of severe thiol depletion and GSH biosynthesis and methionine cycle are upregulated at the expense of ATP but fail to compensate for GSH depletion (311)
