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The text also covers representative drugs of the major biologics currently used in the treatment of HS and describes the IRAK4 inhibitor Zimlovisertib and the IRAK4 degrader KT-474, along with a discussion of the current status of drugs that inhibit IRAK4 in the treatment of HS and the challenges they face

Future research should focus on developing innovative strategies to improve the survival and functionality of implanted stem cells, enhancing the biocompatibility of scaffolds, and identifying the optimal temporal window for molecular cue activation

doi: 10.3390/ph17060775