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The selection of treatment is contingent upon the type and severity of psoriasis, the extent of body surface involvement, patient comorbidities, and the response to prior therapies (Ighani et al
Spiller HA, Krenzelok EP, Grande GA, et al
Preclinical potency benchmark Tomas et al
but also ameliorate the rate of the dialysis and absorption via the gastrointestinal lumen of other water-insoluble amphiphilic substances
