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Description
Trimethylamine-N-Oxide promotes vascular calcification through activation of NLRP3 (nucleotide-binding domain, leucine-rich-containing family, pyrin domain-containing-3) inflammasome and NF-B (nuclear factor B) signals
TMA is synthesized from choline by choline TMA-lyase (CutC)/activator CutD, and from dietary L-carnitine by two processes: 1) One-step conversation of L-carnitine to TMA by carnitine oxygenase/reductase (CntA/B) and 2) by two-step pathway that involves -butyrobetaine (BB)
Wenn Du Dich vegetarisch oder vegan ernhrst, knnte es schwieriger sein, genug Lysin und Methionin aufzunehmen, was die Bildung von L-Carnitin beeintrchtigen knnte
Sun Y, Shu Y, Liu B, Liu P, Wu C, Zheng R, et al
