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Support: Multivitamin One provides the trio of nutrients that support healthy homocysteine metabolism: active folate (methylfolate + folinic acid), active B12 (methylcobalamin + adenosylcobalamin), and vitamin B6all in their bioavailable forms

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Vitamin C sensitizes BRAF(V600E) thyroid cancer to PLX4032 via inhibiting the feedback activation of MAPK/ERK signal by PLX4032

Ethics declarations Ethics approval and consent to participate The experimental procedures in this study were approved by the Ethics Committee of the Reproductive Hospital affiliated with Shandong University (Approval number:2022-73)