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p = 0.012) were significantly higher in maxillofacial surgery patients in comparison with the control group

Therefore, several formulations of curcumin should be assessed to reduce its clinical toxicity and enhance its pharmacokinetic effects

For instance, the depletion of short-chain fatty acids (SCFAs) promotes the polarization of M1 macrophages, which drives intestinal inflammation [36]

10.1016/j.ecl.2009.06.003
