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"Unlike steroids, which are small, cholesterol-based hormones, protein-based hormones or growth factors can easily be destroyed," he wrote in an email

The most important substrates are pyruvate, lactate, glycerol and glucogenic amino acids (especially alanine)
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Missailidis D, Sanislav O, Allan CY, Annesley SJ, Fisher PR

PHGDH inhibits ferroptosis and promotes malignant progression by upregulating SLC7A11 in bladder cancer
