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Description
One of the most useful distinctions from benign Schwann cell tumors is the partial or even complete loss of S100 expression in MPNST[24, 140, 145]

Therapeutic nodal dissection is recommended if nodes are clinically palpable and suspicious for tumor

While not specifically studied with tirzepatide, changes in appetite-regulating hormones that also influence sleep-wake regulation could hypothetically contribute to altered sleep quality during active weight loss phases

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