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In addition, homocysteine can be derived from dietary methionine, which is converted to S-adenosine methionine and is then catalyzed by methyltransferase to produce S-adenosine and further generate homocysteine

While optimal Zn levels confer protective benefits, such as improved insulin sensitivity and reduced oxidative stress, excessive intake triggers systemic inflammation, oxidative damage, and metabolic dysregulation

These results support the findings of other authors, who indicate that, in addition to glutathione, other molecules participate in the antioxidant capacity of yeast extracts ( FIGURE 5 After incubating the yeast biomass subjected to the most intense PEF treatments for 24 h, we obtained an extract with 114.91 2.86, 7.08 0.64, and 187.82 3.75 mg/g dry weight of amino acids, glutathione, and protein, respectively

To this end, buthionine sulphoximine (BSO), which inhibits -glutamylcysteine synthetase 36 , was used to treat T315I-Bcr-Abl-32D cells
