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Description
c-MYC induces ASS1 expression by directly binding its promoter and increasing the intracellular arginine capacity (Tsai et al., 2012)
doi: 10.1111/jcmm.13688
ROS are generated from excessive intracellular iron via the Fenton reaction, which means reactions of Fe 2+ and peroxides to generate oxygen-centered radicals (Winterbourn, 1995)
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