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sFRPs have a Netrin-related motif in the C-terminal region, WIF has a WIF domain in the C-terminal region, and both bind to Wnt proteins, thereby inhibiting Wnt signalling

So, it appears that the extent of the QT effects depends on the baseline of OS and inflammation
3 , 4 , 5 , 6 , 7 , 8 An immunohistochemical study in a RP pig model suggested that the death of rods results in decreased oxygen consumption and hyperoxia in the outer retina resulting in gradual cone cell death from oxidative damage

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