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In order to address this need /the authors/ are advancing /a/preclinical lead, sulfanegen to clinical development
However, some metabolites were also reported to occur in urine of untreated animals, indicating either background contamination via animal feed or endogenous sources, which may limit their suitability as biomarkers of exposure
In the presence of continued oxidative stress, DHA undergoes irreversible degradation to diketogulonic acid which is implicated in the modification and crosslinking of lens proteins [69] (Figure 3)
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