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Folate is critical as a methyl group donor in the 1C metabolism pathway, and adequate folate levels are necessary for proper DNA methylation
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[DOI] [PubMed] [Google Scholar] 38.Jacobson LS, Kirberger RM, Nesbit JW
Mitochondrial respiratory chain complex 1 is targeted by metformin and its inhibition is involved in AMP-activated protein kinase-independent regulation of hepatic gluconeogenesis by triggering alterations in cellular energy charge and redox state
