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Modulation of the immune response with immunosuppressants may interfere with the RAS system and prevent organ damage (96, 97)

SWANN, P.F., KAUFMAN, D.G., MAGEE, P.N., & MACE, R

Additionally, when used in young mice, CAR-T cells were able to persist at considerable levels for up to 12 months post initial treatment and limit the onset of metabolic and physical disorders later in life
