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However, electrochemical methods are marred with major obstacles, including the complex composition of the extracted mixtures, leading to electrode fouling [78]

Because MOTS-c is naturally produced in response to exercise, and because it activates the same AMPK and mitochondrial biogenesis pathways that exercise training upregulates, combining exogenous MOTS-c with a structured exercise program creates a reinforcing signal that operates through the same biological channels

[DOI] [PMC free article] [PubMed] [Google Scholar] 199.Britigan BE, Lewis TS, Waldschmidt M, McCormick ML, Krieg AM