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Effects of glutathione reductase inhibition on cellular thiol redox state and related systems

MTT cell viability assay Organoids were seeded in 96-well plates and cultured for 2 days before treatment with fresh medium containing PHD inhibitors or vehicle control

Typically, transferrin-bound iron predominates, but non-transferrin-bound iron (NTBI) can emerge in plasma during iron overload (Figure 1)

Nelson DB, Mehran RJ, Mitchell KG, Correa AM, Sepesi B, Antonoff MB, Rice DC