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Likewise, stroke-targeting peptides (e.g., CLEVSRKNC) bonded to NPs have also been effectively utilized to deliver neuroprotective drugs to stroke-injured sites in preclinical studies, resulting in decreased infarct size and improved recovery (72)
A first-in-human phase I study of the anticancer stem cell agent ipafricept (OMP-54F28), a decoy receptor for Wnt ligands, in patients with advanced solid tumors
