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Psychiatry Neurol ., 46 , 229230

S1P drives MC activation, which triggers STAT3 activation and the subsequent release of the cell-recruiting chemokines CCL2, CCL3, and CCL5 [127,128]

doi: 10.1016/j.canlet.2013.02.032 66

Interestingly, several persistent clinical manifestation(s) of post-COVID symptoms in PASC patients, sustain as an aftermath from earlier SARS-CoV-2-mediated hijack of host cellular factors (i.e., ACE2, NRP1, furin, TMPRSS2, and CTSL)