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lipoic acid glutathione reductase Effect of alpha-lipoic on oxidative stress parameters: A systematic review and meta-analysis Role of glutathione reductase (GR)
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doi: 10.1038/srep44182 51 JinYWuSZengZFuZ

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5.3 T cell activation by co-stimulatory signals In addition to cytokine and chemokine-mediated regulation, the innate immune system provides essential co-stimulatory signals for T cell activation

Studies on GSTO1-1 also suggested a protective effect of this enzyme on PD, exerted through the inhibition of the active form of interleukin-1 (IL-1 ) which is a critical factor in inflammatory response 47,58
