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Overexpression of redox-regulating enzymes such as thioredoxin and glutamatecysteine ligase in patients with DLBCL has been reported to lead to poor prognosis owing to the ability of tumor cells to cope with oxidative stress from ROS-generating anticancer drugs such as doxorubicin, vincristine, and cyclophosphamide [35]
In parallel, many polymorphisms associated with IR/T2DM intersect pathways that regulate macrophage polarization and stressinflammation signaling, including TLR- and cytokine-dependent networks converging on MAPKJNK, NF-B, and NFE2L2/Nrf2 and related cellular-stress regulators [1227]
The pH, response time, and incubation temperature were all commonly concerned parameters
