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Healthcare providers should know that an allergic reaction is possible if an individual is sensitive to cobalt
However, after oxidative stimulation, the thiol groups of Keap1 undergo covalent modifications, causing its dissociation from Nrf2, which in turn translocates into the nucleus and promotes antioxidant enzyme expression by binding to Antioxidant Response Elements [98,99]

Serine biosynthesis can drive the S-adenosyl methionine (SAM) cycle via one carbon metabolism, thereby fueling the trans-sulfuration pathway and ultimately increasing glutathione production
Zingerone as an antioxidant against peroxynitrite
