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Evaluation of in vitro and in vivo anti-melanogenic activity of a newly synthesized strong tyrosinase inhibitor (E)-3-(2,4 dihydroxybenzylidene)pyrrolidine-2,5-dione (3-DBP)
doi: 10.1021/jf401937b 37 PurcellS.NealeB.Todd-BrownK.ThomasL.FerreiraM
Glutamine binds HSC70 to transduce signals inhibiting IFN--mediated Immunogenic cell death
As vias especficas afetadas incluem a sinalizao da superfamlia TGF-beta, sinalizao Wnt, defesa antioxidante (incluindo superxido dismutase, glutationa S-transferases e tiorredoxina redutase) e mecanismos de reparao de DNA
