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These precursor dermal melanocytes, as they pass through the basement membrane, express E-cadherin which later facilitates intercellular communication with neighbouring keratinocytes in the basal cell layer of the epithelium[1]
Starting low gives you room to adjust upward if needed, but its always best to speak with your clinician first
[12] Wakabayashi, C., Numakawa, T., Ninomiya, M., Chiba, S., & Kunugi, H
PLoS ONE 7(3):e33587
